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Guideline: Generic Neurontin (Gabapentin) – Buy Cheapt and Effective Painkiller

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Generic Neurontin (Gabapentin)

Neurontin (Gabapentin) is a medication that belongs to the class of anticonvulsant drugs. It is an effective painkiller applied in different medical conditions.
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What is Neurontin?

Neurontin, known by its generic name gabapentin, is a pharmaceutical medication belonging to the class of anticonvulsant drugs. It was initially developed to address epileptic seizures, specifically partial seizures, but has since found utility in treating other medical conditions. Neurontin works by affecting certain neurotransmitters and chemicals in the brain, helping to regulate abnormal electrical activity and reduce the occurrence and severity of seizures.

Beyond its primary indication for epilepsy, it has also been approved for the management of neuropathic pain, such as that associated with diabetic neuropathy or postherpetic neuralgia. In this context, it is believed to modulate nerve signaling and provide relief from the discomfort and hypersensitivity often experienced by affected individuals.

Additionally, this medication may be prescribed off-label for conditions like restless leg syndrome, fibromyalgia, and certain anxiety disorders. Off-label use refers to the practice of utilizing a medication for indications not officially approved by regulatory authorities, based on clinical judgment and available evidence.

It is typically available in oral forms, including capsules, tablets, and oral solutions, providing options for flexible dosing and administration. As with any medication, it is important to follow the prescribed dosage and consult with a healthcare professional for guidance, particularly regarding potential side effects, interactions, and individualized treatment plans.


Neurontin (gabapentin) is classified as an anticonvulsant or antiepileptic drug. It was initially developed and approved for the treatment of partial seizures, making it part of the class of medications used to manage epilepsy.

However, Neurontin has also been approved for other conditions such as neuropathic pain, restless leg syndrome, and off-label uses, expanding its classification beyond epilepsy treatment.

Anticonvulsants work by suppressing abnormal electrical activity in the brain, thereby reducing the frequency and severity of seizures. In the case of neuropathic pain, this drug is thought to help regulate overactive nerve signaling and provide relief.

What is neurontin generic name?

The generic name of Neurontin is gabapentin. Gabapentin is an anticonvulsant medication that was originally developed to treat epilepsy. It works by affecting certain chemicals and neurotransmitters in the brain, helping to control seizures and reduce nerve-related pain.

Gabapentin has since been approved for various medical conditions beyond epilepsy, including neuropathic pain, restless leg syndrome, and certain off-label uses. It is available in different dosage forms, including oral capsules, tablets, and oral solutions.

As a generic medication, gabapentin is often more affordable compared to the brand name Neurontin. It is widely available and prescribed by healthcare professionals worldwide. However, it’s important to note that different generic versions of gabapentin may vary slightly in terms of formulation and bioavailability. The specific generic formulation may differ depending on the manufacturer.

Gabapentin is generally well-tolerated, but it can cause side effects such as drowsiness, dizziness, and fatigue. It is important to follow the prescribed dosage and consult a healthcare professional for any concerns or questions regarding its use.

What is Neurontin used for?

Neurontin (gabapentin) is approved by the U.S. Food and Drug Administration (FDA) for specific medical conditions. Here is a list of diseases and conditions commonly used as a treatment:

  1. Epilepsy: Neurontin is FDA-approved as an adjunctive (additional) treatment for partial seizures in adults and children above the age of three.
  2. Neuropathic Pain: Neurontin is commonly prescribed for various types of neuropathic pain, including diabetic neuropathy (nerve damage due to diabetes), postherpetic neuralgia (pain following shingles), and peripheral neuropathy (nerve damage in the extremities).
  3. Fibromyalgia: Neurontin may be used off-label (not FDA-approved) as an adjunctive treatment for fibromyalgia, a chronic disorder characterized by widespread pain, fatigue, and tender points.
  4. Restless Leg Syndrome (RLS): It is sometimes prescribed off-label to manage the uncomfortable sensations and urge to move associated with restless leg syndrome.
  5. Hot Flashes: this drug has been used off-label to help alleviate hot flashes, particularly in menopausal women.
  6. Migraine Prophylaxis: Neurontin is occasionally prescribed off-label as a prophylactic treatment to reduce the frequency and severity of migraines.
  7. Anxiety Disorders: Neurontin may be used off-label to help manage certain anxiety disorders, such as generalized anxiety disorder (GAD) or social anxiety disorder.
  8. Alcohol Withdrawal: This drug can be used off-label to help alleviate symptoms during alcohol withdrawal, such as tremors, anxiety, and seizures.

How does Neurontin work?

Neurontin, also known as gabapentin, exerts its therapeutic effects through its mechanism of action in the central nervous system. While the exact mechanism is not fully understood, several hypotheses have been proposed.

Neurontin is believed to bind to a specific subunit (alpha-2-delta protein) of voltage-gated calcium channels in the brain. By doing so, it modulates the release of various neurotransmitters, including gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter. This modulation leads to a reduction in abnormal electrical activity in the brain, which can help control seizures and alleviate certain types of pain.

Additionally, it is thought to inhibit the release of excitatory neurotransmitters, such as glutamate, and may influence other molecular targets involved in neuronal signaling and plasticity. By modulating these neurotransmitters and signaling pathways, this option contributes to the regulation of neuronal excitability and the modulation of pain perception.

Furthermore, Neurontin’s effects on calcium channels and neurotransmitter release are believed to contribute to its ability to dampen abnormal neuronal firing, reduce hyperexcitability, and ultimately restore a more balanced neuronal activity pattern.

How long does it take Neurontin to work?

The time it takes for Neurontin (gabapentin) to work can vary depending on several factors, including the individual, the medical condition being treated, and the dosage prescribed. It’s important to note that Neurontin is not an immediate-acting medication, and its therapeutic effects may take some time to become noticeable.

For certain conditions like epilepsy, Neurontin may start working within a few days to a couple of weeks, as the body adjusts to the medication and reaches a therapeutic level. However, for conditions such as neuropathic pain, it may take several weeks or even longer for the full benefits of Neurontin to be realized.

It’s worth mentioning that individual responses to this drug can vary. Some individuals may experience a noticeable improvement in their symptoms relatively quickly, while others may require a longer duration of treatment before experiencing significant relief.

How long does Neurontin stay in your system?

The half-life of Neurontin (gabapentin) can vary depending on individual factors such as age, renal function, and other medications being taken. The average half-life in adults with normal renal function is approximately 5 to 7 hours.

To estimate how long Neurontin stays in your system, it’s helpful to consider that it takes approximately five half-lives for a drug to be mostly eliminated from the body. Therefore, it may take around 25 to 35 hours (5 to 7 multiplied by the average half-life) to be eliminated from your system.

It’s important to note that individual variations can occur, and factors such as renal impairment or concomitant use of other medications may affect the elimination rate. It’s always recommended to consult with a healthcare professional for personalized information regarding drug clearance and the duration of Neurontin in your system.

What is the dosage?

The dosage of Neurontin (gabapentin) can vary depending on the specific medical condition being treated, individual patient factors, and the prescribing healthcare professional’s judgment. It’s important to follow the prescribed dosage instructions provided by your healthcare provider. The minimum and maximum doses are typically determined based on the therapeutic goals and tolerability for each patient.

The min dose of Neurontin is generally initiated at a low level and gradually increased to achieve optimal therapeutic effects. This starting dose may be as low as 300 mg per day, divided into multiple doses, and then adjusted based on the individual’s response.

The max dose of Neurontin varies depending on the condition being treated. For epilepsy, the maximum recommended dose is usually around 3600 mg per day, divided into three equal doses. However, for other conditions such as neuropathic pain or restless leg syndrome, the maximum dose may differ.

It’s crucial to note that the specific dosing regimen, including the frequency and duration of the treatment, should be determined by a healthcare professional based on individual needs and medical considerations. The dosage may also be adjusted for individuals with impaired renal function or those requiring concomitant use of certain medications.


An overdose of Neurontin (gabapentin) can occur and may result in various symptoms. It’s important to seek immediate medical attention if an overdose is suspected. The symptoms of an overdose can include:

  1. Drowsiness: Excessive drowsiness or sedation beyond the expected side effects of the medication.
  2. Lethargy: A state of extreme tiredness or lack of energy.
  3. Dizziness: Feeling lightheaded or experiencing a spinning sensation.
  4. Ataxia: Loss of coordination or unsteady movements.
  5. Slurred speech: Difficulty speaking clearly or forming words.
  6. Confusion: Mental disorientation or difficulty thinking clearly.
  7. Nausea and vomiting: Feeling sick to the stomach and potentially vomiting.
  8. Double vision or blurred vision: Visual disturbances or problems with clear vision.

In severe cases, an overdose of Neurontin can lead to respiratory depression, decreased heart rate, or even coma. It’s important to note that the specific symptoms and their severity can vary depending on the amount of this drug taken and individual factors.

What are contraindications?

Strict Contraindications:

  1. Hypersensitivity: Neurontin should not be used in individuals who have a known hypersensitivity or allergic reaction to gabapentin or any of its components. Severe allergic reactions may occur and require immediate medical attention.
  2. Renal Impairment: It is primarily eliminated through the kidneys. Therefore, individuals with severe renal impairment or end-stage renal disease (ESRD) may require dose adjustments or alternative treatments due to the potential accumulation of Neurontin and its metabolites.

Unstrict Contraindications:

  1. Respiratory Depression: While not an absolute contraindication, caution is advised when prescribing Neurontin to individuals with compromised respiratory function or respiratory depression. This drug can cause central nervous system (CNS) depression, which may further impair respiratory function.
  2. Geriatric Patients: Older adults may be more susceptible to the sedative effects of gabapentin, which can increase the risk of falls and cognitive impairment. Dosing adjustments or closer monitoring may be necessary in this population.
  3. Psychiatric Disorders: It may worsen symptoms of depression, anxiety, or other psychiatric disorders in some individuals. Close monitoring is recommended, and adjustments to the treatment plan may be necessary.
  4. Pregnancy and Breastfeeding: While not strictly contraindicated, Neurontin should be used with caution during pregnancy and breastfeeding. The potential risks and benefits should be carefully assessed, and alternative treatments may be considered.
  5. Liver Impairment: It is primarily excreted unchanged in the urine, and liver impairment does not significantly affect its clearance. However, caution may be warranted in individuals with severe liver disease, and dose adjustments may be necessary.

What are the side effects?

Neurontin (gabapentin) may cause various side effects, which can be categorized as common and uncommon. It’s important to note that not everyone will experience these side effects, and the occurrence and severity can vary from person to person. It’s always recommended to consult with a healthcare professional for personalized information and guidance.

Common side effects include:

  1. Drowsiness or sedation: Many individuals may experience drowsiness, which can affect their ability to concentrate or operate machinery safely.
  2. Fatigue: Feeling tired or lacking energy is a common side effect.
  3. Dizziness or lightheadedness: Some people may experience feelings of dizziness or lightheadedness, especially when standing up quickly.
  4. Peripheral edema: Swelling in the hands, feet, or lower legs, known as peripheral edema, can occur in some individuals takingthis substance.
  5. Weight gain: There have been reports of weight gain as a side effect. However, not everyone will experience this.

Uncommon or rare side effects include:

  1. Mood changes: Some individuals may experience mood swings, irritability, or feelings of depression while undergoing this therapy.
  2. Changes in appetite: The described drug may affect appetite, leading to either an increase or decrease in food intake.
  3. Tremor: In rare cases, Neurontin may cause tremors or uncontrollable shaking.
  4. Allergic reactions: Although uncommon, some individuals may experience allergic reactions to this medication, characterized by symptoms such as rash, itching, or swelling.
  5. Cognitive impairment: In rare instances, Neurontin may cause difficulties with memory, concentration, or cognitive function.

What are drug interactions?

Possible drug interactions

Possible Drug Interactions Explanation
Antacids Antacids containing aluminum and magnesium hydroxide may reduce the absorption of Neurontin. It is recommended to separate the administration of the described medication and antacids by at least 2 hours to avoid potential interactions.
Opioids Concurrent use of Neurontin and opioids may increase the risk of central nervous system (CNS) depression, such as drowsiness, sedation, respiratory depression, and even coma. Caution and close monitoring are advised when these medications are used together.
CNS Depressants Other central nervous system (CNS) depressants like benzodiazepines, sedatives, tranquilizers, or alcohol can potentiate the sedative effects of Neurontin, leading to increased drowsiness or impaired coordination. Close monitoring is recommended.
Naproxen Neurontin and naproxen used together may increase the risk of CNS-related side effects such as drowsiness or dizziness. Close monitoring and dose adjustment may be necessary.
Morphine Combining Neurontin with morphine may increase the risk of CNS depression, respiratory depression, and other side effects. Close monitoring and dose adjustment may be required.

Impossible Drug Interactions

Impossible Drug Interactions Explanation
Acetaminophen There are no known significant interactions between Neurontin and acetaminophen. However, it’s important to follow recommended dosage guidelines.
Ibuprofen It does not typically interact with ibuprofen, and they can be used together. Follow recommended dosages and consult a healthcare professional.
Antibiotics Neurontin does not typically interact with most antibiotics. However, it’s always important to consult a healthcare professional or pharmacist for specific antibiotic interactions.
Antidepressants It generally does not have significant interactions with most antidepressants. However, it’s important to consult a healthcare professional for specific antidepressant interactions.
Antihistamines Neurontin does not typically interact with antihistamines. However, it’s always important to follow recommended dosages and consult a healthcare professional if there are any concerns.

What are withdrawal symptoms?

When discontinuing or stopping Neurontin after prolonged use or high-dose treatment, some individuals may experience withdrawal symptoms. It is important to note that not everyone will experience withdrawal symptoms, and the severity and duration can vary from person to person.

Common withdrawal symptoms may include:

  1. Rebound Symptoms: The original symptoms or condition that Neurontin was prescribed for may temporarily resurface or worsen. For example, if Neurontin was being used to manage epilepsy, seizures may become more frequent during withdrawal.
  2. Anxiety and Mood Changes: Some individuals may experience increased anxiety, irritability, mood swings, or depression during the withdrawal.
  3. Insomnia and Sleep Disturbances: Discontinuing Neurontin can disrupt the sleep cycle, leading to difficulty falling asleep, staying asleep, or experiencing vivid dreams.
  4. Nausea and Digestive Issues: Withdrawal from Neurontin can sometimes cause gastrointestinal symptoms such as nausea, stomach discomfort, diarrhea, or constipation.
  5. Physical Discomfort: Headaches, muscle aches, and general feelings of discomfort or malaise may occur during the withdrawal process.

Gabapentin vs Neurontin

Gabapentin and Neurontin are essentially the same medication. Neurontin is the brand name for the drug gabapentin. When a medication is first developed, it is given a generic name, which in this case is gabapentin. Later, pharmaceutical companies may market the medication under a brand name like Neurontin.

Both substances contain the same active ingredient and have the same effects in the body. The main difference lies in the name and packaging. Neurontin is simply the brand name given to gabapentin by the pharmaceutical company Pfizer.

It’s important to note that there may be other generic versions of gabapentin available on the market as well, which would have different brand names. When prescribed by a healthcare professional, it’s always important to confirm the specific medication and follow their instructions regarding its use.

Neurontin pricing

  1. Branded Neurontin:
    • Monthly supply (30 capsules) could range from approximately $100 to $300 or more, depending on the dosage and location.
  2. Generic Gabapentin:
    • Monthly supply (30 capsules) could range from approximately $10 to $100 or more, depending on the dosage and location.


Q: Why is Neurontin a controlled substance?
A: It is not classified as a controlled substance or a narcotic. It is an anticonvulsant medication primarily used to treat epilepsy and neuropathic pain. It does not possess the same potential for abuse or addiction as narcotics.

Q: Neurontin for dogs – yes or no?
A: It can be used for dogs in certain cases, but it is important to note that it should only be administered under the guidance of a veterinarian. The dosage and suitability of Neurontin for dogs will depend on their specific condition and medical history.

Q: Is Neurontin a good painkiller?
A: This drug is often prescribed as an adjunctive treatment for certain types of chronic pain, including neuropathic pain. While it can be effective for some individuals, its effectiveness as a painkiller may vary from person to person. It is recommended to consult with a healthcare professional to determine the best pain management options for specific circumstances.

Q: Does Neurontin make you sleepy?
A: Neurontin may cause drowsiness or sedation as a side effect in some individuals. However, the degree of sleepiness experienced can vary from person to person. It is important to be cautious when operating machinery or engaging in activities that require alertness until you understand how this drug affects you individually.

Q: Neurontin and alcohol
A: Combining Neurontin and alcohol is generally not recommended. Both substances can cause central nervous system depression, which may result in increased drowsiness, dizziness, and impaired coordination. It is advisable to consult with a healthcare professional regarding alcohol consumption while undergoing the treatment.

Q: Does neurontin cause weight gain?
A: Weight gain is a potential side effect associated with Neurontin use. Some individuals may experience an increase in appetite or metabolic changes that can lead to weight gain. However, it is important to note that not everyone who takes this medicine will experience weight gain, and the degree of weight gain can vary among individuals. It is advisable to discuss any concerns about weight changes with a healthcare professional.

Neurontin reviews

John W. (Rating: 4/5)
Neurontin has been a game-changer for me. It effectively reduces my nerve pain and helps me sleep better at night. The only downside is that it occasionally makes me feel a bit drowsy during the day. Overall, a solid medication.

Emily R. (Rating: 3/5)
I’ve been taking Neurontin for a while now, and it does help with my neuropathy pain. However, the side effects can be bothersome. I often experience dizziness and some cognitive fog. It’s a mixed bag for me, but it does provide some relief.

David S. (Rating: 5/5)
Neurontin has been a lifesaver for my chronic migraines. Since I started taking it, the frequency and intensity of my migraines have significantly reduced. I have experienced no major side effects and would highly recommend it to others in a similar situation.

Sarah M. (Rating: 2/5)
Unfortunately, Neurontin didn’t work well for me. I was hopeful it would help with my nerve pain, but I didn’t notice any significant improvement. Additionally, I experienced some unpleasant side effects, including dizziness and nausea. Disappointing.

Michael B. (Rating: 4/5)
Neurontin has been a real game-changer for managing my epilepsy. Since I started taking it, my seizures have become much less frequent. The only downside is that it sometimes makes me feel a little drowsy, but the benefits outweigh the minor inconvenience.

Jennifer L. (Rating: 5/5)
I can’t sing enough praises for Neurontin. It has effectively alleviated my chronic nerve pain and allowed me to regain a semblance of normalcy in my life. I haven’t experienced any notable side effects. Thank you, Neurontin!

Robert K. (Rating: 3/5)
Neurontin has helped me manage my fibromyalgia pain to some extent, but the relief isn’t as significant as I had hoped for. I also noticed some weight gain as a side effect, which was a bit discouraging. It’s worth a try, but results may vary.

Lisa H. (Rating: 4/5)
Neurontin has been a reliable medication for my anxiety and nerve-related anxiety symptoms. It helps calm my nerves without causing any major side effects. The only reason I’m not giving it a perfect score is that it takes a while to kick in during acute episodes.

Disclaimer: The information provided in this article on is intended for informational purposes only and should not be considered as medical advice. The content is not intended to be a substitute for professional medical diagnosis, advice, or treatment. Always consult a healthcare professional before using any medication for erectile dysfunction and discuss any potential risks, side effects, or concerns. The use of any medication carries potential risks and side effects, and individual results may vary. Any potential benefits should be weighed against the potential risks in consultation with a healthcare professional. The author and publisher of this article are not liable for any damages or negative consequences resulting from any person using or relying on the information provided herein.