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Cheap Zanaflex (Tizanidine) Online: Uses, Dosage, Side Effects

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Zanaflex (Tizanidine)

Zanaflex (tizanidine) is a muscle relaxant used used for the short-term treatment of muscle spasticity.
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Muscle spasms can be a persistent and distressing condition, affecting individuals from all walks of life. Finding an affordable and effective medication to alleviate these spasms is crucial for maintaining a good quality of life. Cheap Zanaflex (Tizanidine) offers a cost-efficient solution, and ordering it online provides convenience and potential savings. In this article, we delve into the uses, dosage, and side effects of this drug, highlighting its affordability and discussing important considerations.

Zanaflex (Tizanidine) is a medication widely prescribed to manage muscle spasms caused by various conditions, such as multiple sclerosis, spinal cord injuries, and musculoskeletal disorders. We will explore its therapeutic uses, shedding light on how it effectively targets muscle spasms and restores comfort and mobility.

Understanding the appropriate dosage of this drug is crucial to maximize its benefits while minimizing the risk of side effects. We will provide dosage guidelines and precautions, emphasizing the importance of consulting with a healthcare professional for personalized advice tailored to your specific needs and medical history.

Like any medication, this drug may have potential side effects and interactions. We will discuss common side effects and highlight the importance of being aware of any adverse reactions that may occur. It is essential to understand the possible risks and consult a healthcare professional if you experience any concerning symptoms.

While this article aims to provide general information about Zanaflex, it is crucial to consult with a healthcare professional for personalized medical advice, including proper use, dosage, and potential interactions.

Join us as we explore the uses, dosage, and side effects of cheap generic Zanaflex. By gaining a comprehensive understanding of this medication, you can make informed decisions about its suitability for your muscle spasm management, all while considering affordability and your overall well-being.

What is Zanaflex?

Zanaflex is a medication prescribed for the treatment of muscle spasms. It belongs to a class of drugs called muscle relaxants. zanaflex generic name is tizanidine.

It works by blocking certain nerve signals in the brain and spinal cord, leading to muscle relaxation. It acts on the alpha-2 adrenergic receptors, reducing the intensity and frequency of muscle contractions, and providing relief from muscle spasms and associated pain.

This medication is commonly used to manage muscle spasms caused by conditions such as multiple sclerosis, spinal cord injuries, and musculoskeletal disorders.

It helps improve muscle function, mobility, and overall quality of life for individuals experiencing muscle spasticity.

Tizanidine is available in tablet or capsule form, and the dosage may vary depending on the severity of the spasms and individual response. It is typically taken orally, with or without food. The dosage instructions provided by a healthcare professional should be followed for optimal results.

The drug is available as a brand-name medication and also as a generic version (Tizanidine). The generic version offers a more cost-effective alternative while providing the same therapeutic benefits.

How does Zanaflex work?

The mechanism of action of Zanaflex, also known as Tizanidine, involves its interaction with specific receptors in the central nervous system to alleviate muscle spasms. Zanaflex drug class is a centrally acting alpha-2 adrenergic agonist.

The drug primarily targets alpha-2 adrenergic receptors located in the brain and spinal cord. By binding to these receptors, it modulates the release of neurotransmitters involved in muscle activity and relaxation.

One of the key effects of this drug is the inhibition of excitatory neurotransmitter release, such as norepinephrine. By reducing the activity of excitatory pathways, the pill helps to dampen the excessive nerve signals that contribute to muscle spasms and hyperactivity.

Furthermore, Zanaflex enhances the activity of inhibitory neurotransmitters, such as gamma-aminobutyric acid (GABA). Increased GABA activity helps to further suppress nerve signals and promote muscle relaxation.

The combined action of tizanidine on both inhibiting excitatory neurotransmitters and enhancing inhibitory neurotransmitters contributes to the reduction of muscle spasms and the promotion of muscle relaxation.

Tizanidine’s mechanism of action is localized to the central nervous system, specifically targeting the brain and spinal cord. This allows for a targeted effect on the muscles affected by spasms while minimizing potential effects on other bodily systems.

It is important to note that the exact mechanism of action of this drug is still not fully understood, and further research is ongoing to fully elucidate its effects.

Understanding the mechanism of action of tizanidine provides insights into how the medication works to alleviate muscle spasms. However, it is crucial to consult with a healthcare professional for personalized guidance and monitoring to ensure the safe and effective use of this drug for your specific condition.

What is Zanaflex used for?

Here’s a more detailed table outlining the indications for use of tizanidine Zanaflex:

Indication Description
Multiple Sclerosis (MS) Muscle spasticity associated with multiple sclerosis, characterized by stiffness, spasms, and involuntary muscle contractions. The drug helps improve mobility and reduce spasticity-related pain and discomfort.
Spinal Cord Injuries Muscle spasms and tightness resulting from spinal cord injuries, including traumatic or non-traumatic causes. The drug helps alleviate muscle spasticity, allowing individuals to engage in physical therapy and improve functional abilities.
Musculoskeletal Disorders Muscle spasms related to musculoskeletal disorders such as chronic lower back pain, fibromyalgia, or orthopedic conditions. Zanaflex tizanidine helps reduce muscle tension, alleviate pain, and improve range of motion for enhanced functional capacity.
Other Neurological Conditions Muscle spasticity associated with other neurological conditions, including cerebral palsy, stroke, or traumatic brain injury. The drug helps decrease muscle stiffness, spasms, and involuntary muscle contractions, facilitating better muscle control and movement.
Off-Label Uses The drug may be used off-label for conditions characterized by muscle spasms or spasticity not specifically approved by regulatory authorities but supported by clinical evidence and healthcare professional judgment. It allows for individualized treatment approaches to address specific needs.

Please note that these tablets should be used under the supervision of a healthcare professional, who will assess your specific condition and determine the appropriate indication for use. The dosage, treatment duration, and monitoring will be customized based on individual factors and response to the medication.


For adult individuals suffering from muscle spasticity, Zanaflex should initially be administered at a dose of 2 mg orally, at intervals of 6 to 8 hours as needed, making sure not to exceed 3 doses within a day. The regular dosage may be adjusted within the range of 2 to 4 mg every 6 to 8 hours, with gradual increases of 2 to 4 mg to attain the optimum therapeutic effect. Nonetheless, the daily dosage should not go beyond 36 mg. Special attention is needed when escalating the dose for elderly patients due to a higher susceptibility to adverse reactions.

For pediatric patients between the ages of 6 and 17 suffering from muscle spasticity, the dosage specifics are not readily provided due to inadequate data. It’s therefore recommended to seek advice from a pediatrician to determine the appropriate dosage.

In the case of muscle spasticity patients with kidney issues, the starting dosage remains similar to adults, but adjustments to the dosage need to be done slowly and with continuous monitoring of the patient’s response. The dosage frequency may need to be reduced if necessary. The highest dosage for these patients should be less than the usual maximum dosage as clearance is diminished by over 50% in patients with kidney problems.

For patients with liver conditions, the use of this drug is strongly discouraged due to potential risks and contraindications.

It’s important to reiterate that this is a general guideline. It’s imperative to consult a healthcare provider for personalized medication advice and before initiating, adjusting, or discontinuing any medication regimen.

Instructions for use

When it comes to using Zanaflex, or Tizanidine, it’s imperative that you adhere strictly to your healthcare provider’s instructions. Don’t make any changes to your dosage or stop taking the medication without prior consultation with your healthcare provider. This medication is designed for oral consumption. Therefore, swallow the tablet whole, accompanied by a good amount of water. You have the flexibility to take it either with or without food, but once you decide your preferred method, it’s best to stick to it. The initial dose for adults afflicted with muscle spasticity usually starts at 2 mg, to be taken every 6 to 8 hours as needed.

Your healthcare provider may decide to modify this dosage depending on your medical condition and your response to the drug, with the caveat that the total daily dosage should not exceed 36 mg. It’s beneficial to take the medication at the same times each day, as this helps to maintain a consistent level of the drug in your system and optimizes its effectiveness. Importantly, unless explicitly directed by your healthcare provider, refrain from splitting, crushing, or chewing the tablets, as some versions are designed for slow release of the drug into your system, and breaking the tablet could lead to a sudden release of an excessive amount of the drug. If you miss a dose, take it as soon as you recall. However, if it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not take an extra dose to make up for the missed one. Store the tablets at room temperature, keeping them away from heat, moisture, and direct light, and ensure all medications are out of reach of children. This guidance serves as supplementary information, so make sure to consult with your healthcare provider for more personalized instructions, as they’ll be able to provide advice tailored to your unique health situation.

Zanaflex side effects

The drug can lead to various side effects. Here are some of the side effects that you might experience:

Mild Side Effects:

  • Feeling sleepy or tired.
  • Experiencing dizziness or lightheadedness.
  • Having a dry mouth.
  • Feeling weak or lethargic.
  • Experiencing urinary tract infections.
  • Dealing with constipation.
  • Having abnormal liver function test results.

These side effects are typically mild and often decrease as your body adjusts to the medication. If they persist or worsen, consult with your healthcare provider.

More Serious but Less Common Side Effects:

  • Experiencing hallucinations or delusions.
  • Feeling confused or disoriented.
  • Having a significantly slowed heart rate.
  • Feeling faint or lightheaded, especially upon standing.
  • Dealing with unusual levels of tiredness or weakness.
  • Noticing a change in urine color to a darker shade.
  • Seeing a yellowing of the skin or eyes, a symptom of jaundice.
  • Experiencing signs of an allergic reaction, including a skin rash, severe itching, swelling (particularly of the face, tongue, or throat), extreme dizziness, or difficulties in breathing.

These are serious side effects and are less common. However, if you experience any of them, it is important to seek immediate medical attention.

Rare but Very Serious Side Effects:

  • Experiencing significant changes in mood or mental state, including anxiety, restlessness, or depression.
  • Dealing with severe abdominal or stomach pain.
  • Noticing that your eyes look sunken or that you have dark circles under your eyes.
  • Having a persistent nausea or vomiting.
  • Noticing a decrease in the amount of urine produced.
  • Experiencing a significant weight loss.

These side effects are very serious and quite rare. If you notice any of these symptoms, seek immediate medical help.

Remember, this list does not include all possible side effects. If you observe any other effects not listed above, you should inform your healthcare provider or pharmacist. It’s important to remember that most people who take these pills do not experience serious side effects. Your healthcare provider has prescribed this medication because they believe that the benefits outweigh the potential risks. However, if you have any concerns about these potential side effects, it’s important to communicate with your healthcare provider.

Zanaflex contraindications

Contraindication Description
Hypersensitivity The drug should not be taken by individuals who have a known allergy or intolerance to tizanidine or any other ingredients in the medication.
Severe Liver Disease The drug is metabolized in the liver, and thus, its usage is contraindicated in people with severe liver disease as it could exacerbate their condition.
Concurrent Usage of Certain Medications Zanaflex should not be used by people who are on certain medications like fluvoxamine or ciprofloxacin. These drugs inhibit the enzyme responsible for breaking down tizanidine, which could lead to dangerously high levels of the medication in the blood.
Low Blood Pressure The drug can lower blood pressure, so it should be used with caution in people who already have low blood pressure.
Elderly and People with Kidney Disease Elderly individuals and people with kidney disease may need to have their dose adjusted or need special tests to ensure that they can safely use these tablets.
Pregnancy The use of this drug should be carefully considered in pregnant women due to potential risks to the fetus.
Breastfeeding The drug should be used with caution in breastfeeding women due to potential risks to the nursing baby.
Medications Prolonging QT Interval This drug should be used with caution in individuals taking medications known to prolong the QT interval on the ECG due to increased risk of cardiac arrhythmias.
Uncontrolled Cardiac Conditions The drug should be used with caution in individuals with uncontrolled cardiac conditions such as heart failure, angina, or recent myocardial infarction due to its potential effects on blood pressure.
Use with Alcohol Zanaflex should not be used in combination with alcohol as it can increase its sedative effects and cause excessive drowsiness and impaired motor functions.
Use with Other CNS Depressants This drug should be used with caution in individuals taking other central nervous system depressants due to the increased risk of respiratory depression and sedation.

As always, it’s important to consult with a healthcare provider before beginning any new medication to ensure that it is safe for you to take. They can provide appropriate guidance based on your specific health status and any other medications you are currently taking.

Precautions and warnings

People using muscle relaxer Zanaflex (tizanidine) need to observe certain cautions and heed several warnings for their safety. First and foremost, this drug has the potential to lower blood pressure, especially when doses are ramped up, hence routine checks of blood pressure are recommended for patients using this medication.

Additionally, tizanidine could potentially induce liver damage, especially among those already dealing with liver diseases. Therefore, frequent liver function tests might be required for individuals on this drug. Importantly, this drug can cause a state of drowsiness, which could negatively impact a person’s capacity to operate machinery or drive. Thus, such activities should be avoided until the user understands the medication’s effects on them.

Furthermore, the sedative effects of this medication can be potentiated by alcohol or other central nervous system depressants. It’s advisable for patients to avoid alcohol and exercise caution when using other medications with sedative effects. Also, sudden cessation of tizanidine medication may lead to withdrawal symptoms, such as high blood pressure and rapid heart rate. Hence, it’s recommended to taper off the medication gradually under the supervision of a healthcare professional.

The use of Zanaflex during pregnancy should be weighed carefully due to potential risks to the unborn child. Additionally, it’s not clear whether tizanidine passes into breast milk, so caution is advised for nursing mothers. Elderly individuals and those with kidney diseases may be more prone to the side effects of Zanaflex muscle relaxer, suggesting that dose adjustments may be necessary. Finally, the pill has the potential to interact with a variety of other medications, possibly amplifying the risk of side effects or diminishing its efficacy. Users should always keep their healthcare providers informed about their current medications.

As always, it’s important to consult a healthcare professional before beginning any new medication. They can offer the necessary guidance based on the individual’s unique health circumstances and their existing regimen of medications.

Interactions with other drugs

Here’s a list of some notable drug interactions with Zanaflex (tizanidine):

  1. Blood Pressure Medications: Drugs such as Lisinopril, Amlodipine, and Metoprolol may interact with tizanidine, potentially leading to an excessive decrease in blood pressure. This can cause symptoms such as dizziness, lightheadedness, and fainting.
  2. CNS Depressants: Alcohol, Diazepam, Lorazepam, Alprazolam, Morphine, Oxycodone, Codeine, Amitriptyline, and Doxepin can potentially interact with tizanidine to increase sedation or respiratory depression. This might result in excessive drowsiness, difficulty in breathing, or impaired motor function.
  3. Certain Antibiotics: Ciprofloxacin, Levofloxacin, Moxifloxacin, and Fluvoxamine can increase the concentration of tizanidine in the blood, which could enhance its effectiveness and side effects, including drowsiness and low blood pressure.
  4. Hormonal Therapies: Drugs like Ethinyl estradiol/norethindrone (birth control pills) and Estradiol (hormone replacement therapy) can interfere with the metabolism of tizanidine in the body. This can lead to increased effects or side effects, such as dizziness or dry mouth.
  5. Drugs Metabolized by the Liver: Certain statins like Atorvastatin, Lovastatin, Simvastatin, and Rosuvastatin may interact with Zanaflex medication leading to increased blood levels of these medications. This can potentially amplify their side effects, such as muscle pain or weakness.
  6. Antifungal Medications: Fluconazole, Itraconazole, and Ketoconazole can increase the concentration of tizanidine in the body, which could potentially enhance its effectiveness and side effects.
  7. Antiarrhythmics: Drugs such as Amiodarone, Propafenone, and Quinidine can interact with tizanidine to raise its blood levels, which can enhance the drug’s effectiveness and side effects.

Always remember to consult your healthcare provider or pharmacist about potential drug interactions and keep them informed about all the medications and supplements you’re currently taking.

How to store the drug

Storing the pills correctly is essential to maintain their effectiveness. These pills should be kept at a steady room temperature, ideally between 15°C and 30°C (59°F to 86°F). It’s recommended to store the pills in a tightly closed container, away from sources of heat, light, and moisture, as these can degrade the medicine. Environments that are generally damp or hot, like bathrooms or kitchens, are not recommended for storage. As a safety measure, always ensure that the medicine is stored in a secure place, out of reach of children and pets. If you need to dispose of this drug, don’t just throw it away with the rest of your household waste. Instead, seek advice from your pharmacist or local waste disposal authorities on the correct disposal procedures.

Frequently asked questions

Can I consume alcohol while taking Zanaflex?

A: No, it’s not advisable to consume alcohol while taking this drug as it can increase the medication’s side effects such as drowsiness and dizziness.

What is the maximum Zanaflex dosage?

A: The maximum recommended daily dose is 36mg. However, the dosage will vary based on individual health conditions and the patient’s response to therapy. Always follow your doctor’s instructions regarding dosage.

Can I take Zanaflex with over-the-counter (OTC) medications?

A: Some OTC medications may interact with tizanidine. You should inform your healthcare provider about all medications, supplements, or herbal products you are currently taking.

Is Zanaflex addictive?

A: This medication is not known to be habit-forming; however, abrupt discontinuation after long-term use can lead to withdrawal symptoms. It should always be discontinued under a doctor’s supervision.

Can Zanaflex affect my mental health?

A: The drug can cause side effects such as nervousness, anxiety, or depression in some people. If you experience any changes in your mental health while taking thes tablets, contact your healthcare provider immediately.

Can I take Zanaflex if I have liver disease?

A: Tizanidine is metabolized by the liver and can cause liver damage in some cases. If you have liver disease, discuss this with your healthcare provider before starting these tablets.

How long can I take Zanaflex for?

A: The duration of treatment with this drug varies depending on the patient’s medical condition and response to treatment. Long-term use should be regularly monitored by a healthcare provider.

Can Zanaflex cause constipation?

A: Yes, constipation is a potential side effect of this drug. If you experience persistent constipation while taking this medication, consult your healthcare provider.

What should I do in case of an allergic reaction to Zanaflex 4 mg?

A: If you have signs of an allergic reaction to tizanidine – including hives, difficulty breathing, or swelling of your face, lips, tongue, or throat – seek emergency medical attention.

Flexeril vs Zanaflex: what works better?

Determining whether Flexeril (cyclobenzaprine) or Zanaflex (tizanidine) works better largely depends on the individual patient’s specific condition, overall health, and their body’s response to medication. Both are muscle relaxants, but they are used to treat different types of muscle spasms and have different side effect profiles. Therefore, the decision should be made in consultation with a healthcare provider, who can assess the potential benefits and risks of each drug in relation to the patient’s particular situation.

Is Zanaflex a controlled substance?

This pill is not classified as a controlled substance by the U.S. Drug Enforcement Administration (DEA). This means that it is not considered to have a high potential for abuse or dependence like narcotics or certain other prescription drugs. However, it is still a prescription medication and should only be used under the supervision and guidance of a healthcare professional.

How long does Zanaflex stay in your system?

This medication has a relatively short half-life, averaging around 2.5 hours. This means that it is typically metabolized and eliminated from the body within 12 to 24 hours. However, this can vary based on individual factors such as metabolism, age, liver function, and overall health, potentially leading to a longer or shorter time for this drug to be cleared from the system.

Can I use Zanaflex for anxiety?

The drug is primarily used as a muscle relaxant to help manage muscle spasticity, not as an anxiety medication. While it may have a sedative effect that could potentially help with symptoms of anxiety, it is not specifically approved or commonly used for the treatment of anxiety disorders. Always consult with a healthcare provider for appropriate treatments for conditions like anxiety.

Does Zanaflex make you sleepy?

It is a muscle relaxant that can often cause drowsiness or sedation as a side effect. These effects are due to its action on the central nervous system. While the sedating effects can be beneficial for those dealing with muscle spasticity, they can also interfere with activities that require alertness, such as driving or operating machinery.

Does Zanaflex show up on a drug test?

Standard drug tests, such as those that look for substances like opioids, amphetamines, or benzodiazepines, typically do not include a screen for tizanidine. Therefore, it’s unlikely that this drug would show up on a typical drug test. However, if you’re taking this medication, it’s important to disclose all medications and substances you’re using to the person administering the drug test to avoid any potential confusion or misinterpretation of the results.

How much does Zanaflex cost?

The cost of Zanaflex, or its generic version tizanidine, could vary widely based on the dosage, the pharmacy where it’s purchased, and whether or not you have insurance. In general, generic drugs like tizanidine tend to be less expensive than their brand-name counterparts, but you should check with local pharmacies or your insurance provider for the most accurate and current pricing information.

Is Zanaflex a strong muscle relaxer?

This medication is considered a potent muscle relaxer. It’s primarily used to treat spasticity, a condition characterized by stiff or rigid muscles and spasms, which are often associated with conditions such as multiple sclerosis or spinal cord injury. The drug works by blocking nerve signals that trigger muscle contractions, thus helping to reduce muscle rigidity and spasms. However, its use should be guided by a healthcare professional, as it has potential side effects and interactions with other medications.

How long does Zanaflex last?

Tizanidine is a short-acting muscle relaxant, with its effects typically peaking within 1-2 hours after oral administration. The duration of its therapeutic effects can vary, but generally, they last between 3 to 6 hours, necessitating multiple doses throughout the day for continuous relief of muscle spasticity.

How often can you take Zanaflex?

The frequency of medication administration can vary depending on the individual’s specific condition and their healthcare provider’s instructions. Generally, it can be taken up to three times a day. It’s important to follow the prescribed schedule and dosage instructions given by your healthcare provider, as excessive use can lead to side effects like low blood pressure and sedation.

How does Zanaflex make you feel?

This drug is a muscle relaxant, and its primary effect is to reduce muscle spasticity. This can result in a feeling of relaxation in the muscles. However, it can also cause sedation or a feeling of tiredness in some individuals. Other potential side effects include dry mouth, weakness, and dizziness, which could affect the overall feeling of the individual taking it.

Zanaflex reviews

“Since I’ve started on these pills, my muscle spasms have significantly reduced. I feel a lot more flexible now.” – Brian E.

“Zanaflex 2mg has been a godsend for me. I have a neurological disorder that causes severe muscle stiffness and spasms. This medication has given me a new lease on life. I can now enjoy painting and cooking without having to worry about muscle spasms. The initial drowsiness was slightly bothersome, but it has gotten better over time.” – Grace A.

“The drug does its job in controlling muscle spasms, but the drowsiness it causes is something I’m not too keen on. I plan to talk to my doctor about this.” – Susan D.

“I’ve had muscle spasms due to an old sports injury for years. Nothing seemed to provide any relief until my doctor prescribed this pill. The results were almost immediate and consistent. Yes, there’s some drowsiness, but it’s manageable and worth it for the relief it offers. My life has returned to a sense of normalcy now.” – Stephen T.

“My muscle spasms have considerably reduced since I started on generic Zanaflex 4mg. I couldn’t be happier.” – Angela K.

“I have fibromyalgia and this drug has been great in managing my muscle spasms. It’s made me feel less stiff and in less pain.” – Teresa S.

“After a car accident last year, I was left with recurring muscle spasms that made it hard to cope with daily life. That was until I was prescribed thes pills. This medication has been a great help in providing significant relief. The initial few days were a bit challenging due to the drowsiness, but it has lessened over time. I’m truly thankful for how it’s improved my quality of life.” – Gary P.

“Zanaflex dosage 8 mg has worked wonders for my muscle spasms. Yes, there are some side effects like fatigue, but the benefits outweigh the cons.” – Maria G.

“I have been living with multiple sclerosis for many years, and muscle stiffness has been a constant challenge for me. That was until my doctor prescribed generic Zanaflex pills. This medication has been life-changing. I can perform my daily tasks with ease now. I do feel a bit sleepy sometimes, but I prefer to take it at night, which has worked well for me.” – Lisa W.

“As someone who has suffered from chronic back pain for several years, finding this drug was like finding a beacon of hope. My muscle spasms have significantly reduced and I’ve been able to return to activities I love, like hiking and gardening. It does cause me to feel a bit drowsy at times, but that’s a small price to pay for the immense relief it provides.” – Emily H.

“This medication has truly been a lifeline for me when it comes to managing my muscle spasms. My life has greatly improved since I started on it.” – Mark R.

Disclaimer: The information provided in this article is for informational purposes only and should not be taken as medical advice. The content is not intended as a substitute for professional medical diagnosis, advice or treatment. Always consult a doctor before taking any erectile dysfunction medication and discuss any possible risks, side effects, or concerns. Taking medication comes with risks and possible side effects, and individual results may vary. All potential benefits should be weighed against potential risks in consultation with a healthcare professional. The author and publisher of this article cannot be held liable for any damage or adverse consequences resulting from the use of or reliance on the information provided here.